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Are epsins a therapeutic target for tumor angiogenesis?

Solid tumor growth requires the formation of new blood vessels to supply nutrients and oxygen to the malignant cells; one approach to cancer therapy is to block this process by inhibiting VEGF signaling. In this issue of the JCI, Pasula et al. demonstrate a surprising role of epsins — proteins invol...

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Detalles Bibliográficos
Autor principal: Klauber-DeMore, Nancy
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2012
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533565/
https://ncbi.nlm.nih.gov/pubmed/23187137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66171
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