Endothelial Kruppel-like factor 4 protects against atherothrombosis in mice

The endothelium regulates vascular homeostasis, and endothelial dysfunction is a proximate event in the pathogenesis of atherothrombosis. Stimulation of the endothelium with proinflammatory cytokines or exposure to hemodynamic-induced disturbed flow leads to a proadhesive and prothrombotic phenotype...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhou, Guangjin, Hamik, Anne, Nayak, Lalitha, Tian, Hongmei, Shi, Hong, Lu, Yuan, Sharma, Nikunj, Liao, Xudong, Hale, Andrew, Boerboom, Lauren, Feaver, Ryan E., Gao, Huiyun, Desai, Amar, Schmaier, Alvin, Gerson, Stanton L., Wang, Yunmei, Atkins, G. Brandon, Blackman, Brett R., Simon, Daniel I., Jain, Mukesh K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2012
Schlagworte:
Brief Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533563/
https://ncbi.nlm.nih.gov/pubmed/23160196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66056
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