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Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus

A human polyomavirus was recently discovered in Merkel cell carcinoma (MCC) specimens. The Merkel cell polyomavirus (MCPyV) genome undergoes clonal integration into the host cell chromosomes of MCC tumors and expresses small T antigen and truncated large T antigen. Previous studies have consistently...

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Detalhes bibliográficos
Main Authors: Rodig, Scott J., Cheng, Jingwei, Wardzala, Jacek, DoRosario, Andrew, Scanlon, Jessica J., Laga, Alvaro C., Martinez-Fernandez, Alejandro, Barletta, Justine A., Bellizzi, Andrew M., Sadasivam, Subhashini, Holloway, Dustin T., Cooper, Dylan J., Kupper, Thomas S., Wang, Linda C., DeCaprio, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533549/
https://ncbi.nlm.nih.gov/pubmed/23114601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64116
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