Limitations and possibilities of low cell number ChIP-seq

BACKGROUND: Chromatin immunoprecipitation coupled with high-throughput DNA sequencing (ChIP-seq) offers high resolution, genome-wide analysis of DNA-protein interactions. However, current standard methods require abundant starting material in the range of 1–20 million cells per immunoprecipitation,...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Gilfillan, Gregor D, Hughes, Timothy, Sheng, Ying, Hjorthaug, Hanne S, Straub, Tobias, Gervin, Kristina, Harris, Jennifer R, Undlien, Dag E, Lyle, Robert
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Methodology Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533509/
https://ncbi.nlm.nih.gov/pubmed/23171294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-645
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki