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Importance of UDP-Glucuronosyltransferases 2A2 and 2A3 in Tobacco Carcinogen Metabolism

UDP-glucuronosyltransferase A1 (UGT2A1) is expressed in the lung and exhibits activity against polycyclic aromatic hydrocarbons (PAHs), suggesting UGT2A1 involvement in the local metabolism of PAH tobacco carcinogens. The goal of the present study was to investigate the importance of two additional...

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Autori principali: Bushey, Ryan T., Dluzen, Douglas F., Lazarus, Philip
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533432/
https://ncbi.nlm.nih.gov/pubmed/23086198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.049171
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