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Reversal of Dopamine D2 Agonist-Induced Inhibition of Ventral Tegmental Area Neurons by Gq-Linked Neurotransmitters Is Dependent on Protein Kinase C, G Protein-Coupled Receptor Kinase, and Dynamin

Dopaminergic neurons of the ventral tegmental area are important components of brain pathways related to addiction. Prolonged exposure of these neurons to moderate concentrations of dopamine (DA) decreases their sensitivity to inhibition by DA, a process called DA-inhibition reversal (DIR). DIR is m...

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Detalhes bibliográficos
Main Authors: Nimitvilai, Sudarat, McElvain, Maureen A., Brodie, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533415/
https://ncbi.nlm.nih.gov/pubmed/23019137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.199844
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