Phorbol ester reduces ethanol excitation of dopaminergic neurons of the ventral tegmental area: involvement of protein kinase C theta

Neurons of the ventral tegmental area (VTA) play a key role in the rewarding and reinforcing effects of drugs of abuse, including alcohol. Ethanol directly increases the firing rate of dopaminergic (DAergic) VTA neurons, but modulation of the firing rate of DAergic VTA neurons can be controlled by a...

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Autores principales: Nimitvilai, Sudarat, Arora, Devinder S., You, Chang, McElvain, Maureen, Brodie, Mark S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872320/
https://ncbi.nlm.nih.gov/pubmed/24399942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnint.2013.00096
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