Prasugrel Metabolites Inhibit Neutrophil Functions

Clopidogrel and prasugrel belong to a thienopyridine class of oral antiplatelet drugs that, after having been metabolized in the liver, can inhibit platelet function by irreversibly antagonizing the P2Y(12) receptor. Furthermore, thienopyridines influence numerous inflammatory conditions, but their...

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Hlavní autoři: Liverani, Elisabetta, Rico, Mario C., Garcia, Analia E., Kilpatrick, Laurie E., Kunapuli, Satya P.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2013
Témata:
Inflammation, Immunopharmacology, and Asthma
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533408/
https://ncbi.nlm.nih.gov/pubmed/23097214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.195883
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