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Prasugrel Metabolites Inhibit Neutrophil Functions

Clopidogrel and prasugrel belong to a thienopyridine class of oral antiplatelet drugs that, after having been metabolized in the liver, can inhibit platelet function by irreversibly antagonizing the P2Y(12) receptor. Furthermore, thienopyridines influence numerous inflammatory conditions, but their...

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Detalhes bibliográficos
Main Authors: Liverani, Elisabetta, Rico, Mario C., Garcia, Analia E., Kilpatrick, Laurie E., Kunapuli, Satya P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533408/
https://ncbi.nlm.nih.gov/pubmed/23097214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.195883
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