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Phosphoinositide-Dependent Kinase-1 and Protein Kinase Cδ Contribute to Endothelin-1 Constriction and Elevated Blood Pressure in Intermittent Hypoxia
Obstructive sleep apnea (OSA) is associated with cardiovascular complications including hypertension. Previous findings from our laboratory indicate that exposure to intermittent hypoxia (IH), to mimic sleep apnea, increases blood pressure in rats. IH also increases endothelin-1 (ET-1) constrictor s...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3533405/ https://ncbi.nlm.nih.gov/pubmed/23093023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.195412 |
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