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Endothelin-1-induced vasoconstriction does not require intracellular Ca(2+) waves in arteries from rats exposed to intermittent hypoxia

Sleep apnea is associated with cardiovascular disease, and patients with sleep apnea have elevated plasma endothelin (ET)-1 concentrations. Rats exposed to intermittent hypoxia (IH), a model of sleep apnea, also have increased plasma ET-1 concentrations and heightened constriction to ET-1 in mesente...

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Detalhes bibliográficos
Main Authors: Osmond, Jessica M., Gonzalez Bosc, Laura V., Walker, Benjimen R., Kanagy, Nancy L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949067/
https://ncbi.nlm.nih.gov/pubmed/24414066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00643.2013
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