GTF2IRD2 from the Williams–Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members

GTF2IRD2 belongs to a family of transcriptional regulators (including TFII-I and GTF2IRD1) that are responsible for many of the key features of Williams–Beuren syndrome (WBS). Sequence evidence suggests that GTF2IRD2 arose in eutherian mammals by duplication and divergence from the gene encoding TFI...

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Библиографические подробности
Главные авторы: Palmer, Stephen J., Taylor, Kylie M., Santucci, Nicole, Widagdo, Jocelyn, Chan, Yee-Ka Agnes, Yeo, Jen-Li, Adams, Merritt, Gunning, Peter W., Hardeman, Edna C.
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533390/
https://ncbi.nlm.nih.gov/pubmed/22899722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.102798
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