Detection of Tumor PIK3CA Status in Metastatic Breast Cancer Using Peripheral Blood

PURPOSE: We sought to evaluate the feasibility of detecting PIK3CA mutations in circulating tumor DNA (ctDNA) from plasma of patients with metastatic breast cancer using a novel technique called BEAMing. EXPERIMENTAL DESIGN: In a retrospective analysis, 49 tumor and temporally matched plasma samples...

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Bibliografiset tiedot
Päätekijät: Higgins, Michaela J., Jelovac, Danijela, Barnathan, Evan, Blair, Brian, Slater, Shannon, Powers, Penny, Zorzi, Jane, Jeter, Stacie C., Oliver, George R., Fetting, John, Emens, Leisha, Riley, Carol, Stearns, Vered, Diehl, Frank, Angenendt, Philipp, Huang, Peng, Cope, Leslie, Argani, Pedram, Murphy, Kathleen M., Bachman, Kurtis E., Greshock, Joel, Wolff, Antonio C., Park, Ben H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533370/
https://ncbi.nlm.nih.gov/pubmed/22421194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2696
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