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Eukaryotic elongation factor 2 controls TNF-α translation in LPS-induced hepatitis
Bacterial LPS (endotoxin) has been implicated in the pathogenesis of acute liver disease through its induction of the proinflammatory cytokine TNF-α. TNF-α is a key determinant of the outcome in a well-established mouse model of acute liver failure during septic shock. One possible mechanism for reg...
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| Autores principales: | , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3533299/ https://ncbi.nlm.nih.gov/pubmed/23202732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65124 |
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