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Calcium cycling proteins and heart failure: mechanisms and therapeutics

Ca(2+)-dependent signaling is highly regulated in cardiomyocytes and determines the force of cardiac muscle contraction. Ca(2+) cycling refers to the release and reuptake of intracellular Ca(2+) that drives muscle contraction and relaxation. In failing hearts, Ca(2+) cycling is profoundly altered, r...

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Detalhes bibliográficos
Autor principal: Marks, Andrew R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533269/
https://ncbi.nlm.nih.gov/pubmed/23281409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62834
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