PAR1 contributes to influenza A virus pathogenicity in mice

Influenza causes substantial morbidity and mortality, and highly pathogenic and drug-resistant strains are likely to emerge in the future. Protease-activated receptor 1 (PAR1) is a thrombin-activated receptor that contributes to inflammatory responses at mucosal surfaces. The role of PAR1 in pathoge...

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Bibliographische Detailangaben
Hauptverfasser: Khoufache, Khaled, Berri, Fatma, Nacken, Wolfgang, Vogel, Annette B., Delenne, Marie, Camerer, Eric, Coughlin, Shaun R., Carmeliet, Peter, Lina, Bruno, Rimmelzwaan, Guus F., Planz, Oliver, Ludwig, Stephan, Riteau, Béatrice
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533265/
https://ncbi.nlm.nih.gov/pubmed/23202729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61667
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