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Circadian control of mRNA polyadenylation dynamics regulates rhythmic protein expression

Poly(A) tails are 3′ modifications of eukaryotic mRNAs that are important in the control of translation and mRNA stability. We identified hundreds of mouse liver mRNAs that exhibit robust circadian rhythms in the length of their poly(A) tails. Approximately 80% of these are primarily the result of n...

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Detalhes bibliográficos
Main Authors: Kojima, Shihoko, Sher-Chen, Elaine L., Green, Carla B.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533077/
https://ncbi.nlm.nih.gov/pubmed/23249735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.208306.112
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