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TARDBP mutation analysis in TDP-43 proteinopathies and deciphering the toxicity of mutant TDP-43
The identification of TAR DNA-binding protein 43 (TDP-43) as the major disease protein in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with ubiquitin inclusions (FTLD-U) has defined a new class of neurodegenerative conditions: the TDP-43 proteinopathies. This breakthroug...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3532959/ https://ncbi.nlm.nih.gov/pubmed/22751173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2012-129036 |
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