Cargando...

TARDBP mutation analysis in TDP-43 proteinopathies and deciphering the toxicity of mutant TDP-43

The identification of TAR DNA-binding protein 43 (TDP-43) as the major disease protein in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with ubiquitin inclusions (FTLD-U) has defined a new class of neurodegenerative conditions: the TDP-43 proteinopathies. This breakthroug...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Gendron, Tania F., Rademakers, Rosa, Petrucelli, Leonard
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532959/
https://ncbi.nlm.nih.gov/pubmed/22751173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2012-129036
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!