Clinical significance of large rearrangements in BRCA1 and BRCA2

BACKGROUND: Current estimates of the contribution of large rearrangement (LR) mutations in the BRCA1 (breast cancer 1, early onset) and BRCA2 (breast cancer 2, early onset) genes responsible for hereditary breast and ovarian cancer are based on limited studies of relatively homogeneous patient popul...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Judkins, Thaddeus, Rosenthal, Eric, Arnell, Christopher, Burbidge, Lynn Anne, Geary, Wade, Barrus, Toby, Schoenberger, Jeremy, Trost, Jeffrey, Wenstrup, Richard J, Roa, Benjamin B
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley Subscription Services, Inc., A Wiley Company 2012
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532625/
https://ncbi.nlm.nih.gov/pubmed/22544547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.27556
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