Clinical significance of large rearrangements in BRCA1 and BRCA2

BACKGROUND: Current estimates of the contribution of large rearrangement (LR) mutations in the BRCA1 (breast cancer 1, early onset) and BRCA2 (breast cancer 2, early onset) genes responsible for hereditary breast and ovarian cancer are based on limited studies of relatively homogeneous patient popul...

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Detalhes bibliográficos
Main Authors: Judkins, Thaddeus, Rosenthal, Eric, Arnell, Christopher, Burbidge, Lynn Anne, Geary, Wade, Barrus, Toby, Schoenberger, Jeremy, Trost, Jeffrey, Wenstrup, Richard J, Roa, Benjamin B
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2012
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532625/
https://ncbi.nlm.nih.gov/pubmed/22544547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.27556
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