A robust genomic signature for the detection of colorectal cancer patients with microsatellite instability phenotype and high mutation frequency#

Microsatellite instability (MSI) occurs in 10–20% of colorectal tumours and is associated with good prognosis. Here we describe the development and validation of a genomic signature that identifies colorectal cancer patients with MSI caused by DNA mismatch repair deficiency with high accuracy. Micro...

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Bibliografiske detaljer
Main Authors: Tian, Sun, Roepman, Paul, Popovici, Vlad, Michaut, Magali, Majewski, Ian, Salazar, Ramon, Santos, Cristina, Rosenberg, Robert, Nitsche, Ulrich, Mesker, Wilma E, Bruin, Sjoerd, Tejpar, Sabine, Delorenzi, Mauro, Bernards, Rene, Simon, Iris
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2012
Fag:
Original Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532622/
https://ncbi.nlm.nih.gov/pubmed/22926706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4092
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