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Delving Deeper: MCL-1's Contributions to Normal and Cancer Biology

BCL-2 molecules are regulators of programmed cell death and defects in this pathway contribute to human diseases. One family member, MCL-1, is unique as its expression is tightly regulated and it is essential for promoting the survival of myriad cellular lineages. Additionally, MCL-1 promotes the ma...

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Détails bibliographiques
Auteurs principaux: Perciavalle, Rhonda M., Opferman, Joseph T.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532576/
https://ncbi.nlm.nih.gov/pubmed/23026029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2012.08.011
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