Macrophages modulate cardiac function in lipotoxic cardiomyopathy

Diabetes is associated with myocardial lipid accumulation and an increased risk of heart failure. Although cardiac myocyte lipid overload is thought to contribute to the pathogenesis of cardiomyopathy in the setting of diabetes, the mechanism(s) through which this occurs is not well understood. Incr...

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Main Authors: Schilling, Joel D., Machkovech, Heather M., Kim, Alfred H. J., Schwedwener, Reto, Schaffer, Jean E.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2012
Fag:
Integrative Cardiovascular Physiology and Pathophysiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532539/
https://ncbi.nlm.nih.gov/pubmed/23042950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00111.2012
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