Maternofetal and neonatal copper requirements revealed by enterocyte-specific deletion of the Menkes disease protein

The essential requirement for copper in early development is dramatically illustrated by Menkes disease, a fatal neurodegenerative disorder of early childhood caused by loss-of-function mutations in the gene encoding the copper transporting ATPase ATP7A. In this study, we generated mice with enteroc...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Yanfang, Zhu, Sha, Hodgkinson, Victoria, Prohaska, Joseph R., Weisman, Gary A., Gitlin, Jonathan D., Petris, Michael J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2012
Schlagworte:
Mucosal Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532455/
https://ncbi.nlm.nih.gov/pubmed/23064757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00339.2012
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