Crystal Structure of the Human SUV39H1 Chromodomain and Its Recognition of Histone H3K9me2/3

SUV39H1, the first identified histone lysine methyltransferase in human, is involved in chromatin modification and gene regulation. SUV39H1 contains a chromodomain in its N-terminus, which potentially plays a role in methyl-lysine recognition and SUV39H1 targeting. In this study, the structure of th...

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Detalhes bibliográficos
Main Authors: Wang, Tao, Xu, Chao, Liu, Yanli, Fan, Kai, Li, Zhihong, Sun, Xing, Ouyang, Hui, Zhang, Xuecheng, Zhang, Jiahai, Li, Yanjun, MacKenzie, Farrell, Min, Jinrong, Tu, Xiaoming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532415/
https://ncbi.nlm.nih.gov/pubmed/23285239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052977
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