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Efficient parametric analysis of the chemical master equation through model order reduction

BACKGROUND: Stochastic biochemical reaction networks are commonly modelled by the chemical master equation, and can be simulated as first order linear differential equations through a finite state projection. Due to the very high state space dimension of these equations, numerical simulations are co...

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Hlavní autoři: Waldherr, Steffen, Haasdonk, Bernard
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532330/
https://ncbi.nlm.nih.gov/pubmed/22748204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-81
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