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Efficient parametric analysis of the chemical master equation through model order reduction

BACKGROUND: Stochastic biochemical reaction networks are commonly modelled by the chemical master equation, and can be simulated as first order linear differential equations through a finite state projection. Due to the very high state space dimension of these equations, numerical simulations are co...

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Autors principals: Waldherr, Steffen, Haasdonk, Bernard
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532330/
https://ncbi.nlm.nih.gov/pubmed/22748204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-81
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