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The Ambiguous Role of NKX2-5 Mutations in Thyroid Dysgenesis
NKX2-5 is a homeodomain-containing transcription factor implied in both heart and thyroid development. Numerous mutations in NKX2-5 have been reported in individuals with congenital heart disease (CHD), but recently a select few have been associated with thyroid dysgenesis, among which the p.A119S v...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3532205/ https://ncbi.nlm.nih.gov/pubmed/23285148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052685 |
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