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Biomechanical Stimulation of Osteoblast Gene Expression Requires Phosphorylation of the RUNX2 Transcription Factor
Bone can adapt its structure in response to mechanical stimuli. At the cellular level, this involves changes in chromatin organization, gene expression, and differentiation, but the underlying mechanisms are poorly understood. Here we report on the involvement of RUNX2, a bone-related transcription...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3532028/ https://ncbi.nlm.nih.gov/pubmed/22337141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1574 |
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