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Biomechanical Stimulation of Osteoblast Gene Expression Requires Phosphorylation of the RUNX2 Transcription Factor
Bone can adapt its structure in response to mechanical stimuli. At the cellular level, this involves changes in chromatin organization, gene expression, and differentiation, but the underlying mechanisms are poorly understood. Here we report on the involvement of RUNX2, a bone-related transcription...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3532028/ https://ncbi.nlm.nih.gov/pubmed/22337141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1574 |
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