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Depletion of plasmacytoid dendritic cells inhibits tumor growth and prevents bone metastasis of the breast cancer cells

Elevated levels of plasmacytoid dendritic cells (pDC) have been reported in breast cancer patients, the significance of which remains undefined. Using three different immunocompetent mouse models of BCa bone metastasis, we identified a key role for pDC in facilitating tumor growth through immunosupp...

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Huvudupphovsmän: Sawant, Anandi, Hensel, Jonathan A., Chanda, Diptiman, Harris, Brittney A., Siegal, Gene P., Maheshwari, Akhil, Ponnazhagan, Selvarangan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531993/
https://ncbi.nlm.nih.gov/pubmed/23018462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101855
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