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Noggin Is Novel Inducer of Mesenchymal Stem Cell Adipogenesis: IMPLICATIONS FOR BONE HEALTH AND OBESITY
Noggin is a glycosylated-secreted protein known so far for its inhibitory effects on bone morphogenetic protein (BMP) signaling by sequestering the BMP ligand. We report here for the first time a novel mechanism by which noggin directly induces adipogenesis of mesenchymal stem cells independently of...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3320975/ https://ncbi.nlm.nih.gov/pubmed/22351751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.293613 |
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