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Noggin Is Novel Inducer of Mesenchymal Stem Cell Adipogenesis: IMPLICATIONS FOR BONE HEALTH AND OBESITY

Noggin is a glycosylated-secreted protein known so far for its inhibitory effects on bone morphogenetic protein (BMP) signaling by sequestering the BMP ligand. We report here for the first time a novel mechanism by which noggin directly induces adipogenesis of mesenchymal stem cells independently of...

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Detalhes bibliográficos
Main Authors: Sawant, Anandi, Chanda, Diptiman, Isayeva, Tatyana, Tsuladze, George, Garvey, W. T., Ponnazhagan, Selvarangan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320975/
https://ncbi.nlm.nih.gov/pubmed/22351751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.293613
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