Ethanol withdrawal-induced brain metabolites and the pharmacological effects of acamprosate in mice lacking ENT1

Acamprosate is clinically used to treat alcohol-dependent patients. While the molecular and pharmacological mechanisms of acamprosate remain unclear, it has been shown to regulate γ-aminobutyric acid (GABA) or glutamate levels in the cortex and striatum. To investigate the effect of acamprosate on b...

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Main Authors: Hinton, David J., Lee, Moonnoh R., Jacobson, Taylor L., Mishra, Prasanna K., Frye, Mark A., Mrazek, David A., Macura, Slobodan I., Choi, Doo-Sup
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531991/
https://ncbi.nlm.nih.gov/pubmed/22616110
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