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Acamprosate reduces ethanol drinking behaviors and alters the metabolite profile in mice lacking ENT1
Acamprosate is clinically used to treat alcoholism. However, the precise molecular functionality of acamprosate in the central nervous system remains unclear, although it is known to antagonize glutamate action in the brain. Since elevated glutamate signaling, especially in the nucleus accumbens (NA...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3032037/ https://ncbi.nlm.nih.gov/pubmed/21172405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.12.033 |
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