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Modelling reveals novel roles of two parallel signalling pathways and homeostatic feedbacks in yeast
The high osmolarity glycerol (HOG) pathway in yeast serves as a prototype signalling system for eukaryotes. We used an unprecedented amount of data to parameterise 192 models capturing different hypotheses about molecular mechanisms underlying osmo-adaptation and selected a best approximating model....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
European Molecular Biology Organization
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3531907/ https://ncbi.nlm.nih.gov/pubmed/23149687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2012.53 |
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