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Automated Ensemble Modeling with modelMaGe: Analyzing Feedback Mechanisms in the Sho1 Branch of the HOG Pathway

In systems biology uncertainty about biological processes translates into alternative mathematical model candidates. Here, the goal is to generate, fit and discriminate several candidate models that represent different hypotheses for feedback mechanisms responsible for downregulating the response of...

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Bibliografiske detaljer
Main Authors: Schaber, Jörg, Flöttmann, Max, Li, Jian, Tiger, Carl-Fredrik, Hohmann, Stefan, Klipp, Edda
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068199/
https://ncbi.nlm.nih.gov/pubmed/21483474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014791
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