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TWIST1 is an ERK1/2 effector that promotes invasion and regulates MMP-1 expression in human melanoma cells
Tumor cells often utilize developmental processes in order to progress towards advanced disease. The E-box transcription factor TWIST1 is essential to epithelial-mesenchymal transition and cell migration in the developing neural crest. In melanoma, which derives from the neural crest cell lineage, e...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3531871/ https://ncbi.nlm.nih.gov/pubmed/23222305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-1033 |
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