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Regioselective Reactions of 3,4-Pyridynes Enabled by the Aryne Distortion Model
The pyridine heterocycle continues to play a vital role in the development of human medicines. More than 100 currently-marketed drugs contain this privileged unit, which remains highly sought after synthetically. We report an efficient means to access di- and tri-substituted pyridines in an efficien...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3531798/ https://ncbi.nlm.nih.gov/pubmed/23247178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1504 |
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