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Transglycosylation by Chitinase D from Serratia proteamaculans Improved through Altered Substrate Interactions

We describe the improvement of transglycosylation (TG) by chitinase D from Serratia proteamaculans (SpChiD). The SpChiD produced a smaller quantity of TG products for up to 90 min with 2 mm chitotetraose as the substrate and subsequently produced only hydrolytic products. Of the five residues target...

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Bibliografiske detaljer
Main Authors: Madhuprakash, Jogi, Tanneeru, Karunakar, Purushotham, Pallinti, Guruprasad, Lalitha, Podile, Appa Rao
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531777/
https://ncbi.nlm.nih.gov/pubmed/23115231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.400879
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