Evaluation of Acute Hematologic and Long-Term Pulmonary Toxicities of Radioimmunotherapy of Cryptococcus neoformans Infection in Murine Models

We evaluated acute hematological and long-term pulmonary toxicity of radioimmunotherapy in murine models of Cryptococcus neoformans infection. Activities up to 250 μCi were well tolerated by healthy A/JCr mice for (213)Bi-18B7 and (188)Re-18B7 monoclonal antibodies. In infected mice, doses up to 150...

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Autori principali: Dadachova, E., Bryan, R. A., Frenkel, A., Zhang, T., Apostolidis, C., Nosanchuk, J. S., Nosanchuk, J. D., Casadevall, A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC353163/
https://ncbi.nlm.nih.gov/pubmed/14982795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.3.1004-1006.2004
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