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Reduced Life- and Healthspan in Mice Carrying a Mono-Allelic BubR1 MVA Mutation
Mosaic Variegated Aneuploidy (MVA) syndrome is a rare autosomal recessive disorder characterized by inaccurate chromosome segregation and high rates of near-diploid aneuploidy. Children with MVA syndrome die at an early age, are cancer prone, and have progeroid features like facial dysmorphisms, sho...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3531486/ https://ncbi.nlm.nih.gov/pubmed/23300461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003138 |
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