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Miltefosine Induces Apoptosis-Like Death in Leishmania donovani Promastigotes

Miltefosine (hexadecylphosphocholine [HePC]) has proved to be a potent oral treatment for human visceral leishmaniasis due to Leishmania donovani. The molecular mechanisms that contribute to the antileishmanial activity of HePC are still unknown. We report that in wild-type promastigotes of Leishman...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Paris, Caroline, Loiseau, Philippe M., Bories, Christian, Bréard, Jaqueline
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
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Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353131/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14982775/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.3.852-859.2004
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