Miltefosine Induces Apoptosis-Like Death in Leishmania donovani Promastigotes

Miltefosine (hexadecylphosphocholine [HePC]) has proved to be a potent oral treatment for human visceral leishmaniasis due to Leishmania donovani. The molecular mechanisms that contribute to the antileishmanial activity of HePC are still unknown. We report that in wild-type promastigotes of Leishman...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Paris, Caroline, Loiseau, Philippe M., Bories, Christian, Bréard, Jaqueline
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2004
Soggetti:	Mechanisms of Action: Physiological Effects
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353131/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14982775/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.3.852-859.2004
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