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IFNα and LPS up-regulate APOBEC3 (A3) mRNA through different signaling pathways
APOBEC3 (A3) proteins are virus restriction factors that provide intrinsic immunity against infections by viruses like HIV-1 and MMTV. A3 proteins are inducible by inflammatory stimuli such as LPS and IFNα via mechanisms that are not yet fully defined. Using genetic and pharmacological studies on C5...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3531240/ https://ncbi.nlm.nih.gov/pubmed/22972924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200777 |
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