Proliferation of Genetically Modified Human Cells on Electrospun Nanofiber Scaffolds

Gene editing is a process by which single base mutations can be corrected, in the context of the chromosome, using single-stranded oligodeoxynucleotides (ssODNs). The survival and proliferation of the corrected cells bearing modified genes, however, are impeded by a phenomenon known as reduced proli...

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Detalhes bibliográficos
Main Authors: Borjigin, Mandula, Strouse, Bryan, Niamat, Rohina A, Bialk, Pawel, Eskridge, Chris, Xie, Jingwei, Kmiec, Eric B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Methods - Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530926/
https://ncbi.nlm.nih.gov/pubmed/23212298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2012.51
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