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PATHWAY CROSS-TALK BETWEEN RAS/RAF AND PI3K IN PROMOTION OF M-CSF-INDUCED MEK/ERK-MEDIATED OSTEOCLAST SURVIVAL
While M-CSF-mediated MEK/ERK activation promotes osteoclast survival, the signaling pathway by which M-CSF activates MEK/ERK is unresolved. Functions for PI3K, Ras, and Raf have been implicated in support of osteoclast survival, although interaction between these signaling components has not been ex...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3530847/ https://ncbi.nlm.nih.gov/pubmed/18275061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21719 |
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