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A tumour suppressor network relying on the polyamine–hypusine axis
Tumour suppressor genes encode a broad class of molecules whose mutational attenuation contributes to malignant progression. In the canonical situation, the tumour suppressor is completely inactivated through a two-hit process involving a point mutation in one allele and chromosomal deletion of the...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3530829/ https://ncbi.nlm.nih.gov/pubmed/22722845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11126 |
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