A tumour suppressor network relying on the polyamine–hypusine axis

Tumour suppressor genes encode a broad class of molecules whose mutational attenuation contributes to malignant progression. In the canonical situation, the tumour suppressor is completely inactivated through a two-hit process involving a point mutation in one allele and chromosomal deletion of the...

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Bibliographische Detailangaben
Hauptverfasser: Scuoppo, Claudio, Miething, Cornelius, Lindqvist, Lisa, Reyes, José, Ruse, Cristian, Appelmann, Iris, Yoon, Seungtai, Krasnitz, Alexander, Teruya-Feldstein, Julie, Pappin, Darryl, Pelletier, Jerry, Lowe, Scott W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530829/
https://ncbi.nlm.nih.gov/pubmed/22722845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11126
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