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Targeting the polyamine-hypusine circuit for the prevention and treatment of cancer
The unique amino acid hypusine is present in only two proteins in eukaryotic cells, eukaryotic translation initiation factor 5A-1 (eIF5A1), and eIF5A2, where it is covalently linked to the lysine-50 residue of these proteins via a post-translational modification coined hypusination. This unique modi...
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| Pubblicato in: | Amino Acids |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5573165/ https://ncbi.nlm.nih.gov/pubmed/27357307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-016-2275-3 |
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