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Pharmacokinetics of Posaconazole Coadministered with Antacid in Fasting or Nonfasting Healthy Men

Posaconazole is a potent broad-spectrum azole antifungal agent in clinical development for the treatment of invasive fungal infections. This study evaluated the potential for a pH-dependent pharmacokinetic interaction between posaconazole and an antacid (Mylanta), under fasting and nonfasting condit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Courtney, Rachel, Radwanski, Elaine, Lim, Josephine, Laughlin, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC353067/
https://ncbi.nlm.nih.gov/pubmed/14982768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.3.804-808.2004
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